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1、甲狀腺相關(guān)眼病的臨床分析【摘要】廿的：分析1T1狀腺相關(guān)眼病(thyroidassociatedophthalmopathy,TAO)的臨床特點(diǎn)，為診斷和治療提供依據(jù)。方法：冋顧性分析我院自200107/200710就診的268例473眼TAO患者的臨床資料。結(jié)果:在268例就診的TAO患者中，甲狀腺功能異常者213例(79.5%),眼瞼退縮299眼(63.2%),遲落261眼(55.2%),眼瞼腫脹277眼(58.6%),球結(jié)膜充血、水腫164眼(36.7%),角膜點(diǎn)狀上皮脫落39眼(8.3%),角膜潰瘍8例(1.7%),眼球突出422例(89.2%),眼壓升高
2、者43例(16.0%)69眼(14.6%)，眼球運(yùn)動(dòng)受限332眼(70.2%),其中單方血眼球運(yùn)動(dòng)受限者143眼(43.1%),單方血眼球運(yùn)動(dòng)受限順序依次是下轉(zhuǎn)，內(nèi)轉(zhuǎn)，上轉(zhuǎn),外轉(zhuǎn)，多方面眼球運(yùn)動(dòng)受限者176眼(53.0%),眼球固定13眼(3.9%),M71例(26.5%),影像學(xué)肌肉測(cè)量，眼外肌受累頻率由高到低依次是卜衛(wèi)肌、上立肌、內(nèi)立肌、外立肌，視神經(jīng)病變者31例(11.6%)57眼。結(jié)論：TAO的發(fā)病多與甲腺功能有關(guān)，臨床表現(xiàn)有自身特點(diǎn)，人多數(shù)患者易于診斷，對(duì)于不典型病例要注意眼征特點(diǎn)，眼外肌受累情況以及影像學(xué)意義?！娟P(guān)鍵詞】甲狀腺相關(guān)眼病眼球突出眼內(nèi)壓眼外
3、肌視神經(jīng)ClinicalanalysisofthyroidassociatedophthalmopathyDaWenZheng,HongWang,YanLuoShanxiEyeHospital,Taiyuan030002,ShanxiProvince,ChinaAbstractAIM:Toanalyzetheclinicalcharacteristicofthyroidassociatedophthalmopathy(TAO)soastoprovidebasesforthediagnosisandtreatment.METHODS:Theclinicaldatao
4、f268patients(473eyes)withTAOfromJuly2001toOctober2007inourhospitalwasanalyzedretrospectively.RESULTS:Therewere213eyes(79.5%)ofgkindulathyreoideadisfunction,299eyes(63.2%)oflidretraction,261eyes(55.2%)ofdelayshed,277eyes(5&6%)ofeyelidengorgement,164eyes(36.7%)ofconjunctivalcongestion,d
5、ropsy,39eyes(8.3%)ofkeratodermapunctiformEPIdefluvium,8eyes(1.7%)ofcornealulcer,422eyes(89.2%)ofexophthalmos,69eyes(14.6%)ofintraoculartensionstepupin43patients(16.0%),332eyes(70.2%)ofocularlimitationofmovement.Amongthetotal,onesidedocularlimitationofmovementeyeswere143(43.1%),theorde
6、rofonesidedocularlimitationofmovementwasdeorsumduction,adversion,superductionandexodeviatiortVersatilityocularlimitationofmovementeyeswere176(53.0%),eyeglobefixing13(3.9%),ambiopia71(26.5%);Accordingtomusclemeasureofimageology,thefrequencyofEOMtobeinvolvedfromhightolowwasinferiorrectu
7、s,superiorrectusmuscle,internalrectusmuscle,externalrectusmuscle.Theopticneuropathypatientswere31(11.6%),totally57eyes.CONCLUSION:ThemorbidityofTAOisrelatedtoabnormalthyroidfunction,andtheclinicalmanifestationhasitsowncharacteristics,sothemostcasesareeasytodiagnose.Itisimportanttopaya
8、ttent
